Biomedical Letters

Efficacy of Bioresorbable Vascular Scaffolds as a new Prototype in Case of Coronary Artery Disease: A Review Article

Vidya Sagar Prasad, Ni Jing, Li Weiming*, Xu Yawei

Department of Cardiology, Shanghai 10th People’s Hospital, School of Medicine, Tongji University, Shanghai, 200072, P. R. China

Abstract

Bioresorbable scaffolds (BRS) represent a recent approach in coronary artery stenting technology. In contrast to the metallic stents, they provide transient scaffolding, thereby safeguarding early vessel patency and acute gains at the site of the pre-procedural minimal lumen area. Subsequently, a process of decomposition occurs, that results in the complete absorption of the scaffold, allowing the vessel to maintain its integrity and physiological function. It also minimizes the risk of late complications, allowing the vessel to maintain its integrity and physiological function. This unique ability has attracted much interest and at present several BRS are available. Fully bioresorbable coronary scaffolds function transiently to prevent acute recoil, but it has the potential to inhibit neointima proliferation by eluting drugs. The aim of this review is to describe the advances in the field of the bio-absorbable polymer stent. An overview of the ongoing clinical trials to examine the effectiveness of BRS in the clinical setting has also been evaluated. In order to reduce the rate of clinical events, improvements in the device, as well as implantation procedure, long-term follow-up data is necessary to provide further efficacy and safety.

Keywords: coronary artery disease, bioresorbable vascular scaffold, vascular restoration therapy, restenosis of coronary arteries, absorbable implants.

Received April 22, 2017 Revised May 19, 2017 Accepted May 28, 2017

*Correspondence: Li Weiming Email: ming20390409@qq.com Contact: +8613916499342