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ISSN 2410-955X - An International Biannual Journal
BIOMEDICAL LETTERS
Pulmonary Hypertension in Children with Down Syndrome without Cardiopathy
Ana Belen Ariza Jimenez 1*, Estela Perez Ruiz 1,2, Pilar Caro Aguilera 1,2, Francisco Javier Perez Frias 1,3

1 Pediatrics. Malaga´s Children Hospital. Avda Arroyo de los Angeles s/n 29010. Malaga. Spain
2 Pediatric Pulmonology Unit. Avda Arroyo de los Angeles s/n 29010. Malaga. Spain
Malaga´s University. Avda. Cervantes 2. 29071. Malaga. Spain 

Abstract
Patients with Down syndrome have an increased risk for suffering from pulmonary hypertension, despite not having heart disease, but pathophysiology is rarely known. Those mechanisms justify a low response to nitric oxide, so we explain pathophysiology to explain this response and give other choices of treatments in those cases.

A R T I CL E  I N F O

Received
March 13, 2019
Revised
April 16, 2019
Accepted
April 20, 2019

*Corresponding Author
Ana Belen Ariza Jimenez
E-mail
micodemas@hotmail.com
Contact
+34666154496

Keywords
Oxide nitric
Pulmonary hypertension
Down syndrome
Letter to editor


2019 | Volume 5 | Issue 1