Science Letters

Comparative Effects of Different Local Analgesics and Ketamine on Clinical Parameters for Cranial Epidural Analgesia in Black Bengal goats

Animesh Chandra Roy 1*, Shipra Roy 2, Xiangzhen Shen 2, Muhammad Shahid Bilal 2, Juma Ahamed Abaker Ahamed 3, Hongyu Dai 2, Md. Rafiqul Islam 4

1 Department of Surgery and Theriogenology, Faculty of Veterinary and Animal Science, Sylhet Agricultural University, Sylhet-3100, Bangladesh

2 College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China

3 College of Veterinary Science, Nyala University, Nyala, South Darfur, Sudan

4 Department of Medicine, Faculty of Veterinary and Animal Science, Sylhet Agricultural University, Sylhet-3100, Bangladesh

Abstract

The research was directed to exposing the effect of analgesics on clinical parameter for cranial epidural analgesia in black Bengal goats. A series of thirty-two (32) analgesic trials were conducted in goats aged between 8 to 12 months and with an average body weight of 8.1 kg. Goats were split into four groups (n=4) and a replication of eight trails was implemented in every group at most one week gap. Lignocaine hydrochloride (2%, 6 mg/kg), lignocaine hydrochloride with adrenaline (2%, 6 mg/kg), bupivacaine hydrochloride (0.5%, 1.5 mg/kg) and ketamine hydrochloride (5 mg/kg) were used to perform cranial epidural analgesia. Heart rate, respiration rate, and rectal temperature were examined. Lidocaine hydrochloride significantly (P<0.01) declined the heart rate and significantly (P<0.05) raised respiration rate during cranial epidural analgesia, whereas lidocaine hydrochloride with adrenaline significantly (P<0.01) raised the heart and respiration rate. Bupivacaine hydrochloride non-significantly (P>0.05) raised heart rate and significantly (P<0.01) down turned the respiration rate while ketamine hydrochloride significantly (P<0.01) increased the heart and respiration rate. All anaesthetic agents significantly (P<0.01) declined the rectal temperature during cranial epidural analgesia. The effects of these analgesics on the onset time of anaesthesia, peak time of anaesthesia, area of desensitization and duration of anaesthesia, biochemical and hematological parameter analysis, rumen motility measurement and other tests for enteric response were not performed especially during cranial epidural analgesia in this experiment, this would be of interest in future studies.