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ISSN 2311-3219 - An International Triannual Journal
Acute Recurrent Pancreatitis: An Uncommon Manifestation of Systemic Lupus Erythematosus in children
Aanchal Shrestha, Jingwen Li, Ruochen Che, Zhao Fei*
Deptartment of Nephrology, Nanjing Children's Hospital, Nanjing Medical University, Nanjing 210008, China
Abstract
Systemic lupus erythematosus (SLE) is known as a complex multi-organ autoimmune disorder, which is characterized by systemic inflammation and presents with a variety of clinical manifestations. The relationship of SLE with pancreatitis in children is an uncommon and possibly life-threatening manifestation. Most of the previously reported cases showed that pancreatitis occurs in the setting of SLE with multi-organ involvement. In this report, we present a case of an eleven-year-old girl with the diagnosis of SLE-pancreatitis, which was an acute recurrent pancreatitis phenotype. In our case, pancreatitis was assumed to be a part of SLE exacerbation, accompanied by abnormalities in renal, hematologic and immunology tests. The diagnosis of acute recurrent pancreatitis was based on the signs and symptoms, laboratory tests such as serum and urinary amylase levels and computed tomographic findings. Treatment with high dose steroids and other forms of immunosuppressant drugs showed improvement in the patient. Physicians should consider SLE as an avoidable cause of pancreatitis in any SLE patient with complaints of gastrointestinal symptoms and elevated pancreatic enzymes.
Biomedical Sciences | Case report
A R T I C L E I N F O
Received
May 26, 2018
Accepted
July 19, 2018
Published
Augist 10, 2018
*Corresponding Author
Zhao Fei
E-mail
zhaofei75@163.com
Phone
+86-18951769780
Keywords
Autoimmune disorder
Pancreatitis
Systemic lupus erythematosus
Steroids
2018 | Volume 6 | Issue 2