1 Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Pakistan
2 District Head Quarter Hospital, Chiniot, Pakistan
A Thyroid cancer 1 (TC-1) disordered protein overexpressed in thyroid carcinogenesis mainly to vertebrate, and thyroid cancer associated genes do not have a common homology. Its rate of deaths depends upon the type of thyroid cancer 1. The impact of TC-1 in papillary carcinoma showed more expression of thyroid cancer among other tumors. The protein was involved in various biological processes such as wnt/? catenin signaling pathway involved in thyroid cancer. The TC-1 undergoes a detailed sequence analysis that provides the information in conserved part region among primates, birds, rodents, and reptiles. Additionally, different prediction tools and software were utilized for the prediction of thyroid cancer 1 protein. The string database was used for protein- protein analyses that were performed with LSM1 interacting protein and seek the protein interacting residues by computational approach. The comparative docking was performed by utilizing ZINC library compound and generated an efficient result by selecting the compound having least binding affinity for the analysis of computational drug designing.